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Apoptosis in myocardial infarction | SpringerLink
Dennis V. David B. Gian Antonio Danieli. Walmor C. Francisco A.
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Harry Potter. Popular Features. New Releases. Description Apoptosis or programmed cell death is increasingly considered to be a major factor in the development and progression of cardiovascular disease. In patients with heart failure the activation of apoptosis may result in the loss of irreplaceable cardiac myocytes promoting the clinical course of the syndrome. Moreover, in the coronary arteries inflammation and apoptosis may weaken critical structures of the vessel wall leading to plaque rupture and, subsequently, to myocardial infarction. Given these deleterious consequences, it seems almost paradoxical that programmed cell death is an active process that, if initiated under physiological circumstances, is essential for both coordinated tissue growth or destruction of malignant cells.
Apoptosis in Cardiac Biology, written by a team of internationally renowned researchers, gives a timely synopsis of basic mechanisms, cellular and structural targets and, finally, clinical implications of programmed cell death in the heart. The expert authors of this volume give concise overviews on general and cell-specific aspects of programmed cell death in cardiac myocytes and fibroblasts, as well as in vascular smooth muscle and endothelial cells.
Furthermore, novel therapeutic options arising from the outstanding pathophysiological significance of cardiac apoptosis are presented. This comprehensive review of Apoptosis in Cardiac Biology will be of interest to both clinicians and basic researchers who are active in the fields of cardiology and atherosclerosis. Product details Format Hardback pages Dimensions x x Illustrations note XIV, p.
Other books in this series. Snapshots of Hemodynamics Nico Westerhof. Add to basket. Coronary flow reserve - measurement and application: Focus on transthoracic Doppler echocardiography Pawel Petkow-Dimitrow. Arteriogenesis Wolfgang Schaper. If the address matches an existing account you will receive an email with instructions to retrieve your username.
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